These build instructions should work on:
To build against system wide pEp installation (libs/includes)
python3 setup.py build_ext
To build against a pEp installation in your home dir (libs/includes):
python3 setup.py build_ext --local
To build against a pEp installation in a custom installation root (libs/includes)
python3 setup.py build_ext --prefix=<path_to_your_install_root>
To install the extension module system wide, as root, run:
python3 setup.py install
To install the extension module into you home dir
python3 setup.py install --user
To install the extension module into a custom destination
python3 setup.py install --prefix=<custom_destination_root>